Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.60 |
| ▸ | CTSB | P07858 | 4/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.60 |
| ▸ | CTSK | P43235 | 1/20 | 0.60 |
| ▸ | TACR1 | P25103 | 2/20 | 0.58 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268083 | 0.91 | CTSL (0.62) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL4328694 | 0.88 | CTRB1 (0.53) | CTSLCTSBCTSSCTSK | |
| SCHEMBL16460327 | 0.85 | CTSK (0.63) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL16460328 | 0.85 | CTSK (0.63) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7294146 | 0.84 | CTSL (0.44) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL19807564 | 0.83 | TACR1 (0.72) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10802556 | 0.83 | CTSL (0.70) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7268195 | 0.82 | CTSL (0.63) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL8750890 | 0.81 | CTSL (0.62) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL23819280 | 0.81 | CTSL (0.61) | CTSLCTSBCTSSCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |