Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325702 | 0.89 | ELANE (0.61) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10529734 | 0.89 | ELANE (0.51) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10790451 | 0.88 | CTSK (0.54) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10658214 | 0.87 | CTSK (0.53) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10791828 | 0.83 | ELANE (0.50) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10487578 | 0.80 | CTSK (0.53) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL7323530 | 0.80 | ELANE (0.69) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL20323002 | 0.79 | MEN1 (0.69) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10795035 | 0.78 | CTSK (0.50) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL7330509 | 0.77 | CTSK (0.55) | CTSKCTSLCTSBCTSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098892-A | Angiotensin converting enzyme inhibitors as hypotensive agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| US-4822818-A | ANTIHYPERTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4474692-A | L-Alanyl-N-(indan-2-yl)glycine, its esters and salts thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-10-02 | — | — | US | disclosed |
| EP-0051391-A1 | Bicyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-05-12 | — | — | EP | disclosed |