Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732675 | 0.89 | POLB (0.47) | POLBSTSLMNATSHRESR1 | |
| SCHEMBL9726257 | 0.88 | TSHR (0.54) | POLBSTSLMNATSHRESR1 | |
| SCHEMBL9726266 | 0.83 | ALDH1A1 (0.54) | STSLMNATSHRESR1CYP1A2 | |
| SCHEMBL6763979 | 0.80 | LMNA (0.56) | LMNATSHRESR1CYP1A2CYP2C19 | |
| SCHEMBL9726277 | 0.80 | LMNA (0.56) | POLBSTSLMNATSHRESR1 | |
| SCHEMBL9726267 | 0.79 | PRKCA (0.44) | LMNATSHRSMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL97514 | 0.78 | LMNA (0.79) | STSLMNATSHRESR1CYP1A2 | |
| SCHEMBL28978386 | 0.78 | LMNA (0.79) | STSLMNATSHRESR1CYP1A2 | |
| SCHEMBL1869078 | 0.78 | LMNA (0.79) | STSLMNATSHRESR1CYP1A2 | |
| SCHEMBL22462710 | 0.77 | MAPT (0.67) | STSLMNATSHRESR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5078907-A | UNSYMMETRICAL DICARBOXYLIC ESTERS AS BLEACH PRECURSORS | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1992-01-07 | — | — | US | disclosed |