Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726277 | 0.89 | LMNA (0.56) | SMN1; SMN2ESR1HPGDKMT2AMEN1 | |
| SCHEMBL9726257 | 0.87 | TSHR (0.54) | SMN1; SMN2ESR1HPGDKMT2ARECQL | |
| SCHEMBL9726276 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2CA1CA2CA12CA9 | |
| SCHEMBL9726266 | 0.84 | ALDH1A1 (0.54) | SMN1; SMN2ESR1HPGDKMT2AMEN1 | |
| SCHEMBL9726298 | 0.84 | SLC6A3 (0.54) | SMN1; SMN2CA1CA2CA12CA9 | |
| SCHEMBL38811 | 0.83 | KMT2A (0.58) | SMN1; SMN2ESR1ESR2KMT2AMEN1 | |
| SCHEMBL31098906 | 0.83 | KMT2A (0.58) | SMN1; SMN2ESR1ESR2KMT2AMEN1 | |
| Trimethylammonium SCHEMBL1172450 | 0.83 | ESR1 (0.49) | SMN1; SMN2ESR1ESR2KMT2AMAPT | |
| SCHEMBL11681627 | 0.82 | TSHR (0.41) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL6813788 | 0.79 | TSHR (0.62) | SMN1; SMN2CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5078907-A | UNSYMMETRICAL DICARBOXYLIC ESTERS AS BLEACH PRECURSORS | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1992-01-07 | — | — | US | disclosed |