Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198986 | 0.78 | GABBR2 (0.43) | MEN1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL9726314 | 0.77 | TAS1R3 (0.37) | IKBKETBK1KDM4EGAA | |
| SCHEMBL9195308 | 0.70 | GAA (0.41) | MEN1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL9696441 | 0.68 | MAPT (0.41) | KMT2AIKBKETBK1GAA | |
| SCHEMBL9594192 | 0.65 | MAPT (0.40) | CYP2D6 | |
| SCHEMBL9315021 | 0.64 | KDM4E (0.38) | CYP2C19KDM4E | |
| SCHEMBL9203501 | 0.64 | GABBR2 (0.39) | MEN1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL9196668 | 0.63 | MAPT (0.44) | MEN1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL9200322 | 0.61 | AKR1C3 (0.41) | MEN1CYP2C9CYP2C19KMT2AKDM4E | |
| SCHEMBL6776516 | 0.61 | HPGD (0.41) | MEN1CYP2C9CYP2C19KMT2ATPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4243853-A | — | — | None | — | — | JP | disclosed |
| JP-H04243853-A | NEW 4-AMINOBUTYRIC ACID COMPOUND | ADIR | 1992-08-31 | — | — | JP | disclosed |