SCHEMBL9726995

SCHEMBL9726995

CNc1ccc(Cl)cc1C(=O)c1ccccc1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 1/20 0.64
GABRD O14764 1/20 0.64
GABRA1 P14867 1/20 0.64
GABRB1 P18505 1/20 0.64
GABRG2 P18507 1/20 0.64
GABRB3 P28472 1/20 0.64
GABRA5 P31644 1/20 0.64
GABRA3 P34903 1/20 0.64
GABRA2 P47869 1/20 0.64
GABRB2 P47870 1/20 0.64
GABRA4 P48169 1/20 0.64
GABRE P78334 1/20 0.64
GABRA6 Q16445 1/20 0.64
GABRG1 Q8N1C3 1/20 0.64
GABRG3 Q99928 1/20 0.64
GABRQ Q9UN88 1/20 0.64
RECQL P46063 1/20 0.62
MAPT P10636 4/20 0.62
ALDH1A1 P00352 2/20 0.62
LMNA P02545 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11824528 0.86 GABRP (0.71) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL31384417 0.84 MAPT (0.67) MAPTALDH1A1LMNAKDM4EGLA
SCHEMBL333291 0.84 MAPT (0.67) MAPTALDH1A1LMNAKDM4EGLA
Ethane SCHEMBL11534058 0.83 MAPT (0.65) MAPTALDH1A1LMNAKDM4EGLA
Ammonia Solution, Strong SCHEMBL28210514 0.83 MAPT (0.65) MAPTALDH1A1LMNAKDM4EGLA
SCHEMBL11630143 0.82 GABRP (0.61) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11842389 0.81 RECQL (0.77) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28536564 0.81 ALDH1A1 (0.51) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL19268075 0.80 GABRP (0.63) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL8959210 0.80 ALDH1A1 (0.67) MAPTALDH1A1LMNAKDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111707752-A HPLC detection method of chlordiazepam related substances 山东新华制药股份有限公司 2020-09-25 CN claimed
US-4076702-A 2-O-CHLOROBENZOYL-4-CHLORO-N-METHYL-N(ALPHA)-GLYCYL-GLYCINANILIDE SHIONOGI & CO., LTD. (JA) 1978-02-28 US claimed
CN-111707752-A HPLC detection method of chlordiazepam related substances 山东新华制药股份有限公司 2020-09-25 CN disclosed
WO-2008120235-A1 NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2008-10-09 WO disclosed
US-5091415-A Antiulcer, antisecretory agents PIERRE FABRE MEDICAMENT (FR) 1992-02-25 US disclosed
US-5025015-A Antisecretory and antiulcer agents PIERRE FABRE MEDICAMENT (FR) 1991-06-18 US disclosed
US-4476061-A ANXIOLYTIC AGENTS PIERRE FABRE, SA (FR) 1984-10-09 US disclosed
US-4409241-A Method of treating anxiety with 2'-(orthochlorobenzoyl)-4'-chloroglycylanilides, and compositions thereof PIERRE FABRE S.A. (FR) 1983-10-11 US disclosed
US-4382930-A 2'-(Orthochlorobenzoyl)-4'-chloroglycylanilides, compositions thereof, and use as medicaments PIERRE FABRE S.A. (FR) 1983-05-10 US disclosed
US-4380667-A ANXIOLYTIC AGENTS PIERRE FABRE S.A. (FR) 1983-04-19 US disclosed
US-4370347-A Method of treating anxiety with 2'-(orthochlorobenzoyl)-4'-chloroglycylanilides, and compositions thereof PIERRE FABRE S.A. (FR) 1983-01-25 US disclosed
US-4240957-A FOR USE AS SEDATIVES, MUSCLE RELAXANTS, HYPNOTICS, ANTICONVULSANTS, AND TRANQUILIZERS SHIONOGI & CO., LTD. (JP) 1980-12-23 US disclosed
US-4154727-A REACTING A GLYCINAMIDE WITH A HALOACETYL HALIDE SHIONOGI & CO., LTD. (JP) 1979-05-15 US disclosed
US-4096144-A Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-06-20 US disclosed
US-4076703-A 2-O-CHLOROBENZOYL-4-CHLORO-N-METHYL-N(ALPHA)-GLYCYL-GLYCINANILIDE SHIONOGI & CO., LTD. (JA) 1978-02-28 US disclosed
US-4076704-A 2-O-CHLOROBENZOYL-4-CHLORO-N-METHYL-N(ALPHA)-GLYCYL-GLYCINANILIDE SHIONOGI & CO., LTD. (JA) 1978-02-28 US disclosed
US-4076702-A 2-O-CHLOROBENZOYL-4-CHLORO-N-METHYL-N(ALPHA)-GLYCYL-GLYCINANILIDE SHIONOGI & CO., LTD. (JA) 1978-02-28 US disclosed
US-4076705-A 2-O-CHLOROBENZOYL-4-CHLORO-N-METHYL-N(ALPHA)-GLYCYL-GLYCINANILIDE SHIONOGI & CO., LTD. (JA) 1978-02-28 US disclosed