Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.61 |
| ▸ | GABRD | O14764 | 2/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.61 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.61 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.61 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.61 |
| ▸ | GABRE | P78334 | 2/20 | 0.61 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.61 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.61 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.61 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457524 | 0.84 | MAPT (0.62) | MAPTCYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL9726995 | 0.82 | GABRP (0.64) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11824528 | 0.81 | GABRP (0.71) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12165506 | 0.80 | TSHR (0.52) | MAPTCYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL12165535 | 0.79 | IRAK4 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11842389 | 0.79 | RECQL (0.77) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11866382 | 0.78 | MAPT (0.55) | RECQLMAPTCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL9851141 | 0.77 | RECQL (0.74) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2991610 | 0.77 | GABRP (0.78) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11061295 | 0.76 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082764-A | Methods for the production of 4H-s-triazolo[4,3-a][1,4]benzodiazepine 5N-oxides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-04-04 | — | — | US | disclosed |