Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 4/20 | 0.47 |
| ▸ | MMP8 | P22894 | 3/20 | 0.47 |
| ▸ | MMP14 | P50281 | 2/20 | 0.47 |
| ▸ | PGK1 | P00558 | 2/20 | 0.46 |
| ▸ | PGK2 | P07205 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22652869 | 0.78 | PTPRC (0.49) | LMNAPTPRCMMP2MMP8PGK1 | |
| SCHEMBL19638012 | 0.77 | ACP3 (0.58) | CYP1A2LMNAMAPTTHRBPMP22 | |
| [Bromo(Phenyl)Methyl]Phosphonic Acid SCHEMBL2418538 | 0.77 | SRC (0.60) | PTPRCPGK1PGK2 | |
| SCHEMBL4093802 | 0.77 | SRC (0.60) | CYP1A2LMNAMAPTTHRBPMP22 | |
| (4-Chlorophenyl)(Hydroxy)Methylphosphonic Acid SCHEMBL5746553 | 0.76 | PGK1 (0.59) | CYP1A2LMNAMAPTTHRBPMP22 | |
| (4-Chlorophenyl)(Hydroxy)Methylphosphonic Acid SCHEMBL292744 | 0.76 | PGK1 (0.59) | CYP1A2LMNAMAPTTHRBPMP22 | |
| SCHEMBL9204375 | 0.76 | PGK1 (0.82) | CYP1A2LMNAMAPTTHRBPMP22 | |
| SCHEMBL11497064 | 0.74 | CYP1A2 (0.55) | CYP1A2LMNAMAPTTHRBPMP22 | |
| SCHEMBL5623742 | 0.74 | PGK1 (0.78) | CYP1A2LMNAMAPTTHRBPMP22 | |
| SCHEMBL31060679 | 0.74 | CYP1A2 (0.50) | CYP1A2LMNAMAPTTHRBPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110734364-A | Synthesis method of 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone | 上海生农生化制品股份有限公司 | 2020-01-31 | — | — | CN | disclosed |
| US-5089511-A | Trifluoromethylvinyl compounds | ROUSSEL UCLAF (FR) | 1992-02-18 | — | — | US | disclosed |
| US-4920231-A | Reacting with trifluoroacetic acid with halovinyl compound in presence of cuprous salt | ROUSSEL UCLAF (FR) | 1990-04-24 | — | — | US | disclosed |