Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538321 | 0.86 | SIGMAR1 (0.49) | ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL9536801 | 0.85 | POLB (0.39) | — | |
| SCHEMBL9727271 | 0.83 | ALDH1A1 (0.61) | ALDH1A1KMT2ASIGMAR1P2RX7 | |
| SCHEMBL9538045 | 0.80 | DRD1 (0.48) | ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL9534996 | 0.79 | OPRK1 (0.40) | — | |
| SCHEMBL9535279 | 0.79 | PLA2G1B (0.36) | ALDH1A1 | |
| SCHEMBL9538607 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KMT2ASIGMAR1ERCC1ERCC4 | |
| SCHEMBL8317694 | 0.77 | KMT2A (0.43) | ALDH1A1KMT2ASIGMAR1ERCC1ERCC4 | |
| SCHEMBL8317467 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2ASIGMAR1ERCC1ERCC4 | |
| SCHEMBL9535638 | 0.76 | TACR1 (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |