Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299175 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1MAPK1TSHRPOLB | |
| SCHEMBL9658290 | 0.86 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1MAPK1TSHRPOLB | |
| SCHEMBL7843059 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1MAPK1TSHRPOLB | |
| SCHEMBL12368644 | 0.82 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1MAPK1TSHRPOLB | |
| Trifluoromethanesulfonic Acid SCHEMBL29356486 | 0.80 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1MAPK1TSHRPOLB | |
| SCHEMBL9659962 | 0.80 | L3MBTL1 (0.43) | SMN1; SMN2ALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL11008582 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1MAPK1TSHRPOLB | |
| SCHEMBL2175797 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL7419507 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MAPK1TSHRPOLB | |
| SCHEMBL29557286 | 0.76 | SIRT1 (0.53) | SMN1; SMN2ALDH1A1MAPK1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144027-A | Cephalosporins, process for producing the same, intermediates thereof and process for producing the intermediates | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| US-4879381-A | ANTIBIOTICS | TOYOMA CHEMICAL COMPANY, LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| US-4717767-A | ANTIBIOTICS | TOYAMA CHEMICAL CO., LTD. (JP) | 1988-01-05 | — | — | US | disclosed |
| US-4673738-A | Novel intermediates of cephalosporins and process for producing 7-(substituted or unsubstituted amino)-3-substituted methyl-Δ3 -cephem-4-carboxylic acids | HANDI-PAC INC. (US) | 1987-06-16 | — | — | US | disclosed |
| US-4618606-A | Antibiotic 7-(thiazolyl)-3-(pyrazinylmethyl) or (pyridazinylmethyl) cephalosporins | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| US-4489072-A | BACTERICIDE, ANTIBIOTIC | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-12-18 | — | — | US | disclosed |