Hydrochloric Acid

Hydrochloric Acid

SCHEMBL9727394

CCCCCCCCCCCCCCCCCCOCCOCC[N+](CCC)(CCC)CCC.[Cl-]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.54
MEN1 O00255 1/20 0.54
THRB P10828 1/20 0.54
KMT2A Q03164 1/20 0.54
MAPT P10636 1/20 0.54
PRKD3 O94806 1/20 0.44
PRKCG P05129 1/20 0.44
PRKCB P05771 1/20 0.44
PRKCA P17252 1/20 0.44
PRKCH P24723 1/20 0.44
PRKCI P41743 1/20 0.44
PRKCE Q02156 1/20 0.44
PRKCQ Q04759 1/20 0.44
PRKCZ Q05513 1/20 0.44
PRKCD Q05655 1/20 0.44
PRKD1 Q15139 1/20 0.44
SLC22A1 O15245 4/20 0.44
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31302310 0.86 SLC22A1 (0.62) HTTMEN1THRBKMT2AMAPT
SCHEMBL24465404 0.84 DNM1 (0.58) HTTMEN1THRBKMT2AMAPT
Hydrochloric Acid SCHEMBL31302283 0.84 SLC22A1 (0.59) HTTMEN1THRBKMT2AMAPT
Bromide SCHEMBL20547415 0.84 ALDH1A1 (0.64) HTTMEN1THRBKMT2AMAPT
SCHEMBL8045306 0.83 SLC22A1 (0.62) HTTMEN1THRBKMT2AMAPT
Hydrochloric Acid SCHEMBL10482450 0.83 HTT (0.61) HTTMEN1THRBKMT2AMAPT
SCHEMBL3300264 0.82 SLC22A1 (0.62) HTTMEN1THRBKMT2AMAPT
SCHEMBL23356804 0.81 THRB (0.75) HTTMEN1THRBKMT2AMAPT
SCHEMBL23356781 0.81 THRB (0.75) HTTMEN1THRBKMT2AMAPT
SCHEMBL23356862 0.81 THRB (0.75) HTTMEN1THRBKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE34062-E Mixture of water insoluble cationic surfactant and fatty acid LEVER BROTHERS COMPANY (US) 1992-09-15 US disclosed
US-4308024-A CATIONIC SURFACTANT AND FATTY ACID LEVER BROTHERS COMPANY (US) 1981-12-29 US disclosed
US-4173539-A QUATERNARY AMMONIUM SALT LEVER BROTHERS COMPANY (US) 1979-11-06 US disclosed