Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727536 | 0.84 | TSHR (0.59) | GAATP53TSHRAKR1C3MMP2 | |
| SCHEMBL7383735 | 0.79 | MMP2 (0.64) | GAATP53MMP2 | |
| SCHEMBL9727635 | 0.78 | GAA (0.46) | GAATP53AKR1C3MMP2 | |
| SCHEMBL9727409 | 0.77 | TP53 (0.48) | GAATP53MMP2 | |
| SCHEMBL7379601 | 0.75 | MMP2 (0.64) | GAATP53AKR1C3MMP2 | |
| SCHEMBL10702282 | 0.75 | MMP2 (0.64) | GAATP53AKR1C3MMP2 | |
| SCHEMBL7380549 | 0.75 | PKM (0.62) | GAATP53AKR1C3MMP2 | |
| SCHEMBL9727293 | 0.75 | TP53 (0.59) | GAATP53 | |
| SCHEMBL9727624 | 0.75 | GAA (0.48) | GAATP53AKR1C3MMP2 | |
| SCHEMBL25348950 | 0.74 | MMP2 (0.62) | GAATP53MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164514-A | Antispasmodics | ROUSSEL UCLAF (FR) | 1992-11-17 | — | — | US | disclosed |
| US-5081130-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1992-01-14 | — | — | US | disclosed |
| US-4990531-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1991-02-05 | — | — | US | disclosed |
| EP-0335758-A2 | Derivatives of 1-arylsulfonyl-2-pyrolidinone, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1989-10-04 | — | — | EP | disclosed |