Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 9/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698874 | 1.00 | GCGR (0.41) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9698112 | 0.88 | GCGR (0.44) | GCGRRPS6KA3CYP1A2CYP2C19 | |
| SCHEMBL9523672 | 0.84 | GCGR (0.40) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9791356 | 0.84 | GCGR (0.40) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8949683 | 0.83 | GCGR (0.53) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8949786 | 0.79 | GCGR (0.47) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9380517 | 0.79 | RXRA (0.47) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9383069 | 0.77 | GCGR (0.39) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9735571 | 0.77 | GCGR (0.39) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9728453 | 0.76 | GCGR (0.40) | GCGRESR1HMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120782-A | Treatment of hyperlipoproteinaemia, lipoproteinaemia and arteriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-09 | — | — | US | disclosed |