Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728857 | 0.88 | DPP4 (0.32) | DPP4NR1H2NR1H3ANPEP | |
| SCHEMBL9728180 | 0.84 | DPP4 (0.42) | DPP4NR1H2NR1H3ANPEPALDH1A1 | |
| SCHEMBL9728307 | 0.79 | TSHR (0.50) | DPP4NR1H2NR1H3ANPEPALDH1A1 | |
| SCHEMBL9728643 | 0.75 | DPP4 (0.39) | DPP4NR1H2NR1H3ANPEPALDH1A1 | |
| SCHEMBL9728387 | 0.68 | DPP4 (0.36) | DPP4NR1H2NR1H3ANPEPALDH1A1 | |
| SCHEMBL9729088 | 0.67 | CRHBP (0.34) | DPP4ANPEPALDH1A1 | |
| SCHEMBL11863751 | 0.67 | HTR1A (0.40) | ALDH1A1TSHR | |
| SCHEMBL9728918 | 0.67 | ALDH1A1 (0.46) | DPP4NR1H2NR1H3ANPEPALDH1A1 | |
| SCHEMBL5600840 | 0.66 | PTGS2 (0.41) | ALDH1A1TSHR | |
| SCHEMBL9728553 | 0.66 | DPP4 (0.42) | DPP4NR1H2NR1H3ANPEPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406163-A1 | Thioxotetrazolines | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | claimed |
| US-5138068-A | Pesticide | CIBA-GEIGY CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |
| US-5066667-A | Controlling insects and arachnids | CIBA-GEIGY CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0406163-A1 | Thioxotetrazolines | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |