Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.73 |
| ▸ | MEN1 | O00255 | 7/20 | 0.73 |
| ▸ | TSHR | P16473 | 4/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.61 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.61 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728467 | 0.83 | RAB9A (0.72) | KDM4EKMT2AMEN1TSHRNPSR1 | |
| SCHEMBL10916324 | 0.80 | KDM4E (0.71) | KDM4EKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL9728402 | 0.78 | RAB9A (0.57) | KDM4EKMT2AMEN1TSHRNPSR1 | |
| SCHEMBL11703846 | 0.78 | KDM4E (1.00) | KDM4EKMT2AMEN1TSHRNPSR1 | |
| SCHEMBL9728648 | 0.76 | ADORA3 (0.57) | KDM4ENPSR1TP53RAB9ATDP1 | |
| SCHEMBL29850001 | 0.76 | MAP3K7 (0.83) | KDM4EKMT2AMEN1TSHRNPSR1 | |
| SCHEMBL9728645 | 0.76 | RAB9A (0.61) | KDM4EKMT2AMEN1TSHRNPSR1 | |
| SCHEMBL11705345 | 0.76 | KDM4E (0.91) | KDM4EKMT2AMEN1TSHRNPSR1 | |
| SCHEMBL20063046 | 0.74 | MAP3K7 (1.00) | KDM4EKMT2AMEN1TSHRNPSR1 | |
| SCHEMBL29722841 | 0.74 | MAP3K7 (1.00) | KDM4EKMT2AMEN1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | claimed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |