Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.72 |
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728645 | 0.92 | RAB9A (0.61) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL9728472 | 0.84 | KDM4E (0.57) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL29510945 | 0.84 | RAB9A (1.00) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL14773948 | 0.84 | RAB9A (1.00) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL9728402 | 0.83 | RAB9A (0.57) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL9728156 | 0.83 | KDM4E (0.73) | RAB9ANPC1KDM4EALDH1A1PDE11A | |
| SCHEMBL9728648 | 0.82 | ADORA3 (0.57) | RAB9ANPC1KDM4ETP53NPSR1 | |
| SCHEMBL9728470 | 0.80 | RAB9A (0.68) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL17916715 | 0.79 | RAB9A (0.89) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL10004321 | 0.77 | KDM4E (0.58) | RAB9ANPC1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | claimed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |