Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707540 | 0.83 | RAB9A (0.69) | ADORA3RAB9ANPC1MAPK1TP53 | |
| SCHEMBL9728467 | 0.82 | RAB9A (0.72) | ADORA3RAB9ANPC1TP53KDM4E | |
| SCHEMBL9728402 | 0.80 | RAB9A (0.57) | ADORA3RAB9ANPC1TP53KDM4E | |
| SCHEMBL9728156 | 0.76 | KDM4E (0.73) | RAB9ANPC1MAPK1TP53KDM4E | |
| SCHEMBL9728645 | 0.75 | RAB9A (0.61) | ADORA3RAB9ANPC1MAPK1TP53 | |
| SCHEMBL11702096 | 0.75 | RAB9A (0.65) | ADORA3RAB9ANPC1MAPK1TP53 | |
| SCHEMBL5089620 | 0.75 | RAB9A (0.70) | RAB9ANPC1TP53KDM4ENPSR1 | |
| SCHEMBL4401440 | 0.74 | ADORA3 (1.00) | ADORA3ADORA2AADORA1 | |
| SCHEMBL27810320 | 0.72 | KDM4E (0.62) | RAB9ANPC1MAPK1POLBKDM4E | |
| SCHEMBL24090010 | 0.72 | USP2 (0.52) | RAB9ANPC1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | claimed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |