Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 7/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728206 | 0.83 | HTT (0.36) | CTSKCTSLCTSBHTTCTSS | |
| SCHEMBL10436315 | 0.79 | FOLH1 (0.49) | PKMSMN1; SMN2CTSLHTTCTSS | |
| SCHEMBL10436316 | 0.79 | FOLH1 (0.49) | PKMSMN1; SMN2CTSLHTTCTSS | |
| SCHEMBL1799613 | 0.79 | PKM (0.46) | PKMSMN1; SMN2CTSLHTTCTSS | |
| SCHEMBL9728155 | 0.78 | PKM (0.45) | PKMSMN1; SMN2HTTCTSS | |
| SCHEMBL16488037 | 0.76 | CTSS (0.50) | PKMSMN1; SMN2CTSKCTSLCTSB | |
| SCHEMBL13593497 | 0.75 | CTSS (0.51) | PKMSMN1; SMN2CTSKCTSLCTSB | |
| SCHEMBL1839729 | 0.72 | CTSS (0.69) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL1328599 | 0.71 | SIRT6 (0.44) | CTSK | |
| SCHEMBL10421632 | 0.71 | GSR (0.38) | CTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | claimed |