Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728158 | 0.83 | PKM (0.45) | HTTCTSLCTSKCTSBCTSS | |
| SCHEMBL9728204 | 0.78 | ALDH1A1 (0.35) | HTTALDH1A1POLBCTSSDPP7 | |
| SCHEMBL9728202 | 0.78 | ALDH1A1 (0.35) | HTTALDH1A1POLBCTSSDPP7 | |
| SCHEMBL1328599 | 0.74 | SIRT6 (0.44) | CTSKDPP7DPP8DPP9 | |
| SCHEMBL10421632 | 0.71 | GSR (0.38) | CTSLCTSKCTSBDPP7DPP8 | |
| SCHEMBL13128069 | 0.71 | GSR (0.38) | CTSLCTSKCTSBDPP7DPP8 | |
| SCHEMBL13049054 | 0.70 | CTSK (0.43) | CTSK | |
| SCHEMBL22297887 | 0.69 | CTSK (0.38) | CTSLCTSKCTSBDPP7DPP8 | |
| SCHEMBL20333850 | 0.69 | CTSK (0.43) | CTSLCTSKCTSBDPP7DPP8 | |
| SCHEMBL26016842 | 0.69 | KDM4E (0.43) | HTTALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | claimed |