Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439069 | 0.91 | — | — | |
| SCHEMBL4248602 | 0.82 | PIK3CD (0.39) | PIK3CDKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL9463026 | 0.80 | L3MBTL1 (0.47) | PIK3CDALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL658992 | 0.78 | L3MBTL1 (0.50) | PIK3CDALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL18513375 | 0.78 | PIK3CD (0.42) | PIK3CDKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL14276924 | 0.78 | PYGL (0.39) | PIK3CDALDH1A1LMNA | |
| SCHEMBL3483367 | 0.78 | DPP4 (0.37) | — | |
| SCHEMBL2932705 | 0.77 | — | — | |
| SCHEMBL9462350 | 0.77 | ADH1A (0.47) | PIK3CDALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL1416138 | 0.77 | ALOX5 (0.42) | ALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5157034-A | Neuroleptic perhydro-1H-pyrido[1,2-a]pyrazines | PFIZER INC. (US) | 1992-10-20 | — | — | US | disclosed |