Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728779 | 0.91 | MAPK1 (0.43) | MAPTMAPK1PKML3MBTL1ALDH1A1 | |
| SCHEMBL9193373 | 0.91 | PKM (0.51) | MAPTMEN1KMT2AMAPK1PKM | |
| SCHEMBL9728757 | 0.91 | PKM (0.41) | MAPTMEN1KMT2AMAPK1PKM | |
| SCHEMBL9198733 | 0.86 | POLB (0.40) | MAPTMEN1KMT2AMAPK1PKM | |
| SCHEMBL9728372 | 0.85 | MAPT (0.41) | MAPTKMT2AMAPK1PKML3MBTL1 | |
| SCHEMBL9196221 | 0.83 | MAPT (0.46) | MAPTMEN1KMT2AMAPK1PKM | |
| SCHEMBL10102444 | 0.77 | CYP19A1 (0.52) | MAPTKMT2A | |
| SCHEMBL9728699 | 0.75 | KCNQ2 (0.41) | MAPTMEN1KMT2AMAPK1PKM | |
| SCHEMBL9196029 | 0.75 | L3MBTL1 (0.51) | MAPTMEN1KMT2AMAPK1PKM | |
| SCHEMBL9196693 | 0.72 | ADRB2 (0.43) | MAPTMEN1KMT2APKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151421-A | Compounds for inhibition of metabolism of retinoids, for treatment for proliferation of epithelial cells and keratin disorders | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-09-29 | — | — | US | disclosed |
| US-5028606-A | Retinoid metabolism inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-07-02 | — | — | US | disclosed |