Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.42 |
| ▸ | TUBB | P07437 | 4/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728418 | 0.84 | ADRB2 (0.53) | KDM4EALDH1A1HPGDHSD17B10TOP2A | |
| SCHEMBL10435765 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL5541223 | 0.77 | TOP2A (0.55) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL19751491 | 0.77 | TOP2A (0.55) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL2339241 | 0.77 | TOP2A (0.55) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL30306119 | 0.77 | TOP2A (0.55) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL20125115 | 0.77 | TOP2A (0.55) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9728544 | 0.77 | ADRB2 (0.44) | KDM4EALDH1A1HPGDHSD17B10TOP2A | |
| SCHEMBL10413345 | 0.77 | TOP2A (0.50) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL13663766 | 0.77 | TOP2A (0.50) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153203-A | QUINOLONE DERIVATIVES AND SALTS THEREOF, PREPARATION PROCESSES THEREOF, AND ANTIBACTERIAL AGENTS CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1992-10-06 | — | — | US | disclosed |