Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728418 | 0.85 | ADRB2 (0.53) | ADRB2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29576844 | 0.78 | KMT2A (0.60) | ADRB2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4306583 | 0.78 | KMT2A (0.60) | ADRB2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9728447 | 0.77 | KDM4E (0.43) | ADRB2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL22497602 | 0.77 | KDM4E (0.44) | ADRB2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9728493 | 0.77 | CACNA1F (0.41) | ADRB2ALDH1A1LMNAKMT2ATOP2B | |
| SCHEMBL13080499 | 0.76 | BTK (0.43) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL13080527 | 0.76 | BTK (0.43) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL4296349 | 0.75 | ADRB2 (0.47) | ADRB2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10577000 | 0.75 | KMT2A (0.54) | ADRB2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153203-A | QUINOLONE DERIVATIVES AND SALTS THEREOF, PREPARATION PROCESSES THEREOF, AND ANTIBACTERIAL AGENTS CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0390215-A2 | Quinolone derivatives and salts thereof, preparation process es thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-03 | — | — | EP | disclosed |