Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 12/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728401 | 0.90 | CACNA1F (0.51) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9728418 | 0.85 | ADRB2 (0.53) | POLBKCNH2TOP2ATOP2BADRB2 | |
| SCHEMBL9728445 | 0.83 | MEN1 (0.38) | POLBBTKMEN1ALDH1A1LMNA | |
| SCHEMBL1344898 | 0.78 | STAT3 (0.54) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9728544 | 0.77 | ADRB2 (0.44) | TOP2ATOP2BADRB2BTKALDH1A1 | |
| SCHEMBL5704363 | 0.75 | GSK3B (0.51) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6880793 | 0.75 | GSK3B (0.50) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9728559 | 0.74 | TOP2A (0.49) | POLBKCNH2TOP2ATOP2BMEN1 | |
| SCHEMBL9688633 | 0.73 | CACNA1F (0.49) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9728447 | 0.73 | KDM4E (0.43) | POLBTOP2ATOP2BADRB2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153203-A | QUINOLONE DERIVATIVES AND SALTS THEREOF, PREPARATION PROCESSES THEREOF, AND ANTIBACTERIAL AGENTS CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0390215-A2 | Quinolone derivatives and salts thereof, preparation process es thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-03 | — | — | EP | disclosed |