Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728096 | 0.92 | EPHX1 (0.66) | ALDH1A1MAPTALOX12KMT2AKDM4E | |
| SCHEMBL9728569 | 0.86 | ALDH1A1 (0.74) | ALDH1A1MAPTALOX12KMT2AKDM4E | |
| SCHEMBL5451832 | 0.83 | ALDH1A1 (0.80) | ALDH1A1MAPTALOX12KMT2AKDM4E | |
| SCHEMBL9729024 | 0.78 | ALDH1A1 (0.80) | ALDH1A1MAPTALOX12KMT2AKDM4E | |
| SCHEMBL9818510 | 0.77 | ALDH1A1 (0.76) | ALDH1A1MAPTALOX12KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL3714476 | 0.76 | KMT2A (0.68) | ALDH1A1MAPTKMT2ARAB9ANPC1 | |
| SCHEMBL8708055 | 0.75 | ALDH1A1 (0.73) | ALDH1A1MAPTALOX12KMT2AKDM4E | |
| SCHEMBL29661164 | 0.75 | ALDH1A1 (0.71) | ALDH1A1MAPTALOX12KMT2ARAB9A | |
| SCHEMBL2344119 | 0.75 | ALDH1A1 (0.71) | ALDH1A1MAPTALOX12KMT2ARAB9A | |
| SCHEMBL9728074 | 0.74 | ALDH1A1 (0.70) | ALDH1A1MAPTALOX12KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | disclosed |