Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4521778 | 0.78 | GAA (0.64) | HPGDHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10445383 | 0.76 | ALDH1A1 (0.45) | HPGDALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9728468 | 0.75 | PPARG (0.48) | CYP1A2CYP2C9MAPT | |
| SCHEMBL10378288 | 0.73 | PPARG (0.58) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9728623 | 0.73 | MAPT (0.58) | CYP1A2CYP2C9MAPT | |
| SCHEMBL5338385 | 0.70 | HPGD (0.67) | HPGDHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11296924 | 0.70 | HPGD (0.55) | HPGDHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10560020 | 0.69 | ALOX15 (0.50) | HPGDHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5350551 | 0.69 | RAB9A (0.76) | HPGDALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL33527951 | 0.68 | POLB (0.64) | HPGDHSD17B10ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155106-A | Reduced side effects | TERUMO KABUSHIKI KAISHA (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0400144-A1 | CYSTEAMINE DERIVATIVES AND ANTI-RHEUMATIC AGENT CONTAINING SAME | TERUMO KABUSHIKI KAISHA (JP) | 1990-12-05 | — | — | EP | disclosed |