Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.58 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344881 | 0.78 | APP (0.54) | ADORA3APPSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL627899 | 0.77 | FGFR1 (0.65) | — | |
| SCHEMBL31040239 | 0.77 | FGFR1 (0.65) | — | |
| SCHEMBL9728941 | 0.77 | NPC1 (0.67) | MAOBADORA2ANPC1PKMRAB9A | |
| SCHEMBL20427956 | 0.77 | LMNA (0.48) | ADORA3ABCG2MAOBADORA2ANPC1 | |
| SCHEMBL31347645 | 0.75 | APP (0.61) | ADORA3APPABCG2KDM4EALDH1A1 | |
| SCHEMBL2395706 | 0.75 | APP (0.61) | ADORA3APPABCG2KDM4EALDH1A1 | |
| SCHEMBL29044810 | 0.74 | APP (0.60) | ADORA3APPSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29033598 | 0.74 | ADORA3 (0.62) | ADORA3APPKDM4EALDH1A1HPGD | |
| SCHEMBL31060760 | 0.73 | ADORA3 (1.00) | ADORA3NPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | disclosed |