Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728494 | 0.81 | CHRM2 (0.45) | CHRM2CHRM4CHRM5ADRA2AADRA2B | |
| SCHEMBL9728716 | 0.80 | CHRM2 (0.41) | CHRM2CHRM4CHRM5ADRA2AADRA2B | |
| SCHEMBL9729003 | 0.78 | CHRM2 (0.40) | CHRM2CHRM4CHRM5ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL9728899 | 0.78 | CHRM2 (0.42) | CHRM2CHRM4CHRM5ADRA2AADRA2B | |
| SCHEMBL9728143 | 0.75 | CHRM2 (0.38) | CHRM2CHRM4CHRM5ADRA2AADRA2B | |
| SCHEMBL9729439 | 0.75 | MAOA (0.39) | — | |
| Hydrochloric Acid SCHEMBL9728714 | 0.73 | CHRM2 (0.37) | CHRM2CHRM4CHRM5ADRA2AADRA2B | |
| SCHEMBL9728485 | 0.73 | DRD2 (0.43) | KCNH2SIGMAR1 | |
| SCHEMBL9728112 | 0.69 | RAD52 (0.43) | — | |
| SCHEMBL10869454 | 0.69 | SIGMAR1 (0.45) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128340-A | Thiazole derivatives | AKZO N.V. (NL) | 1992-07-07 | — | — | US | disclosed |
| EP-0372125-A1 | Oxazole and thiazole derivatives | AKZO N.V. (NL) | 1990-06-13 | — | — | EP | disclosed |
| EP-0368384-A1 | Thiazole derivatives | AKZO N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |