Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728485 | 0.90 | DRD2 (0.43) | MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL9728509 | 0.85 | THRB (0.39) | — | |
| SCHEMBL9728783 | 0.84 | KDM4E (0.46) | MAOAKDM4EMEN1ALDH1A1GLA | |
| SCHEMBL9728716 | 0.82 | CHRM2 (0.41) | — | |
| SCHEMBL9728112 | 0.79 | RAD52 (0.43) | — | |
| SCHEMBL9728399 | 0.79 | CHRM1 (0.35) | CHRM1 | |
| SCHEMBL9451990 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2ATAAR1 | |
| SCHEMBL9728521 | 0.76 | MAPT (0.41) | KDM4EALDH1A1MAPT | |
| SCHEMBL9728927 | 0.75 | CHRM2 (0.43) | — | |
| SCHEMBL9728317 | 0.75 | CHRM1 (0.55) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128340-A | Thiazole derivatives | AKZO N.V. (NL) | 1992-07-07 | — | — | US | disclosed |
| EP-0372125-A1 | Oxazole and thiazole derivatives | AKZO N.V. (NL) | 1990-06-13 | — | — | EP | disclosed |
| EP-0368384-A1 | Thiazole derivatives | AKZO N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |