Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686559 | 0.81 | BRD4 (0.49) | BRD4SCN9AALDH1A1HDAC1HDAC8 | |
| SCHEMBL9842340 | 0.80 | CHRM1 (0.38) | BRD4ALDH1A1CHRM1KDM4EMAPT | |
| SCHEMBL39263 | 0.79 | CHRM1 (0.35) | BRD4ALDH1A1CHRM1MAPT | |
| SCHEMBL12188290 | 0.79 | HTR1A (0.37) | CHRM1 | |
| SCHEMBL9687801 | 0.78 | BRD4 (0.57) | BRD4SCN9AALDH1A1ALOX15CHRM1 | |
| SCHEMBL9685790 | 0.76 | BRD4 (0.53) | BRD4SCN9AALDH1A1HDAC1HDAC8 | |
| SCHEMBL7965666 | 0.75 | MAPT (0.37) | BRD4SCN9AALDH1A1HDAC1HDAC6 | |
| SCHEMBL7965670 | 0.75 | MAPT (0.37) | BRD4SCN9AALDH1A1HDAC1HDAC6 | |
| SCHEMBL9685904 | 0.75 | BRD4 (0.49) | BRD4SCN9AALDH1A1ALOX15MAPT | |
| SCHEMBL9685812 | 0.73 | BRD4 (0.51) | BRD4SCN9AALDH1A1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084084-A | Uracil and thiouracil derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0408382-A2 | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1991-01-16 | — | — | EP | disclosed |