Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39263 | 0.85 | CHRM1 (0.35) | CHRM1BRD4CHRM5CHRM3RORC | |
| SCHEMBL12188290 | 0.84 | HTR1A (0.37) | CHRM1 | |
| SCHEMBL9728989 | 0.80 | BRD4 (0.47) | CHRM1BRD4TSHRKDM4EMAPT | |
| SCHEMBL9427952 | 0.78 | CHRM1 (0.40) | CHRM1BRD4CHRM5CHRM3RORC | |
| SCHEMBL9478242 | 0.75 | KMO (0.32) | CHRM1BRD4TSHR | |
| SCHEMBL8986639 | 0.74 | CHRM1 (0.39) | CHRM1BRD4CHRM5CHRM3RORC | |
| SCHEMBL7563867 | 0.74 | NR3C2 (0.39) | TP53MAPTPOLB | |
| SCHEMBL9032890 | 0.74 | CHRM1 (0.32) | CHRM1RORC | |
| SCHEMBL8914465 | 0.72 | BCAT1 (0.37) | — | |
| SCHEMBL9385393 | 0.72 | ALDH1A1 (0.35) | CHRM1BRD4CHRM5CHRM3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420194-A2 | Uracil derivatives and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |