Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17774703 | 0.92 | RAPGEF4 (0.39) | RAPGEF4HSD17B10ALDH1A1RECQLKDM4E | |
| SCHEMBL17774704 | 0.90 | HSD17B10 (0.37) | RAPGEF4HSD17B10ALDH1A1RECQLKDM4E | |
| SCHEMBL9138977 | 0.88 | HSD17B10 (0.44) | RAPGEF4HSD17B10ALDH1A1RECQLKDM4E | |
| SCHEMBL17774684 | 0.86 | HSD17B10 (0.39) | RAPGEF4HSD17B10ALDH1A1RECQLKDM4E | |
| SCHEMBL9138818 | 0.85 | HSD17B10 (0.43) | RAPGEF4HSD17B10ALDH1A1RECQLKDM4E | |
| SCHEMBL7809571 | 0.83 | PTGER4 (0.46) | RAPGEF4HSD17B10ALDH1A1RECQLKDM4E | |
| SCHEMBL8951824 | 0.81 | HSD17B10 (0.37) | RAPGEF4HSD17B10ALDH1A1RECQLKDM4E | |
| SCHEMBL4816515 | 0.81 | MAPT (0.40) | RAPGEF4HSD17B10ALDH1A1RECQLKDM4E | |
| SCHEMBL8745461 | 0.80 | ALDH1A1 (0.42) | RAPGEF4HSD17B10ALDH1A1RECQLKDM4E | |
| SCHEMBL10630292 | 0.79 | KMT2A (0.41) | RAPGEF4HSD17B10ALDH1A1RECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160143826-A1 | PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION | L'OREAL (FR) | 2016-05-26 | — | — | US | disclosed |
| US-5093483-A | WATER-SOLUBLE AZO COMPOUNDS HAVING A 6-CARBOXY-2-NAPHTHAL AS COUPLING COMPONENTS, SUITABLE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160143826-A1 | PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION | KRT18, ARSA, SQOR | RAPGEF4 4858/4885HSD17B10 529/4885ALDH1A1 440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.