Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | RECQL | P46063 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8951824 | 0.89 | HSD17B10 (0.37) | ALDH1A1RECQLHSD17B10TSHRTHRB | |
| SCHEMBL9811303 | 0.87 | CA2 (0.45) | ALDH1A1RECQLHSD17B10TSHRTHRB | |
| SCHEMBL9682315 | 0.86 | RAPGEF4 (0.42) | ALDH1A1RECQLHSD17B10TSHRTHRB | |
| SCHEMBL9558736 | 0.86 | CA2 (0.41) | ALDH1A1HSD17B10THRBCA2MAPT | |
| SCHEMBL9809387 | 0.86 | RAPGEF4 (0.42) | ALDH1A1RECQLHSD17B10TSHRTHRB | |
| SCHEMBL8008676 | 0.84 | ALDH1A1 (0.44) | ALDH1A1RECQLHSD17B10TSHRTHRB | |
| SCHEMBL6937844 | 0.84 | L3MBTL1 (0.40) | ALDH1A1RECQLHSD17B10TSHRTHRB | |
| SCHEMBL10948058 | 0.84 | HSD17B10 (0.38) | ALDH1A1RECQLHSD17B10TSHRTHRB | |
| SCHEMBL5675279 | 0.84 | CYP3A4 (0.36) | ALDH1A1RECQLHSD17B10TSHRTHRB | |
| SCHEMBL6878401 | 0.82 | ALDH1A1 (0.39) | ALDH1A1RECQLTHRBCYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160143826-A1 | PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION | L'OREAL (FR) | 2016-05-26 | — | — | US | disclosed |
| WO-1997043345-A1 | REACTIVE AZO DYES WITH A REACTIVE-ANCHOR-CARRYING DIAZO COMPONENT FROM THE SERIES OF M-PHENYLENE DIAMINE | ZAMPONI, ANDREA | 1997-11-20 | — | — | WO | disclosed |
| EP-0694588-A1 | Triphendioxazine reactive dyes, preparation and use thereof | BAYER AG (DE) | 1996-01-31 | — | — | EP | disclosed |
| US-5453501-A | Phthalocyanine reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1995-09-26 | — | — | US | disclosed |
| EP-0582886-A1 | Phthalocyanine reactive dyes | BAYER AG (DE) | 1994-02-16 | — | — | EP | disclosed |
| EP-0356681-B1 | DISAZO DYES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0357915-B1 | DISAZO DYES | BAYER AG (DE) | 1993-04-28 | — | — | EP | disclosed |
| US-5003053-A | Water-soluble monoazo compounds containing a p-aminophenylamino- and chloro- or fluoro-substituted triazinylamino group and a fiber-reactive group selected from the vinylsulfone series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-26 | — | — | US | disclosed |
| EP-0357915-A1 | Disazo dyes | BAYER AG (DE) | 1990-03-14 | — | — | EP | disclosed |
| EP-0356681-A1 | Disazo dyes | BAYER AG (DE) | 1990-03-07 | — | — | EP | disclosed |
| EP-0279351-A2 | Water soluble azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160143826-A1 | PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION | KRT18, ARSA, SQOR | ALDH1A1 440/4885RECQL 3312/4885HSD17B10 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.