Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30339701 | 0.82 | L3MBTL1 (0.52) | MEN1KMT2AMAOBADRA2BALDH1A1 | |
| SCHEMBL30339822 | 0.79 | ALOX12 (0.49) | ALOX12MEN1KMT2AMAOBALDH1A1 | |
| SCHEMBL5180846 | 0.79 | MEN1 (0.53) | ALOX12MEN1KMT2AADRA2BALDH1A1 | |
| SCHEMBL5537895 | 0.78 | KDM1A (0.46) | KDM1AALOX12MEN1KMT2AMAOB | |
| SCHEMBL11513654 | 0.77 | KMT2A (0.72) | ALOX12MEN1KMT2AMAOBALDH1A1 | |
| SCHEMBL26697159 | 0.77 | RAB9A (0.62) | ALOX12MEN1KMT2AMAOBALDH1A1 | |
| SCHEMBL24147765 | 0.76 | ALOX12 (0.46) | ALOX12MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL149179 | 0.76 | CA12 (0.64) | ALOX12MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5537898 | 0.76 | KDM1A (0.50) | KDM1AALOX12MEN1KMT2AALDH1A1 | |
| SCHEMBL16211512 | 0.75 | PPARA (0.49) | ALOX12MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081241-A | Diabetes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |