Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2965399 | 0.81 | AKR1B1 (0.55) | AKR1B1MAPT | |
| SCHEMBL26697130 | 0.80 | AKR1B1 (0.62) | ALDH1A1AKR1B1POLBKMT2AHPGD | |
| SCHEMBL9729006 | 0.77 | KDM1A (0.54) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL26697146 | 0.77 | NPC1 (0.53) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL26697143 | 0.77 | AKR1B1 (0.56) | RAB9ANPC1ALDH1A1AKR1B1KMT2A | |
| SCHEMBL21834398 | 0.77 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17200823 | 0.77 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2LMNAMAOB | |
| SCHEMBL27942151 | 0.76 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2MAOBPOLB | |
| SCHEMBL4489127 | 0.76 | P2RX7 (0.54) | AKR1B1 | |
| SCHEMBL28559896 | 0.76 | KMT2A (0.63) | RAB9ANPC1SMN1; SMN2LMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119212999-A | Pyrrolopyrimidine compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-12-27 | — | — | CN | disclosed |
| CN-117164591-A | Pyrrolopyrimidine compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2023-12-05 | — | — | CN | disclosed |
| WO-2023226580-A1 | PYRROLOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 中国医学科学院药物研究所 | 2023-11-30 | — | — | WO | disclosed |