Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28794446 | 0.91 | MAPT (0.64) | MAPTNPSR1L3MBTL1MAPK1CYP2D6 | |
| SCHEMBL23376910 | 0.91 | MAPT (0.64) | MAPTNPSR1L3MBTL1MAPK1CYP2D6 | |
| SCHEMBL7306734 | 0.88 | MAPT (0.47) | MAPTNPSR1L3MBTL1MAPK1CYP2D6 | |
| SCHEMBL7306746 | 0.88 | MAPT (0.47) | MAPTNPSR1L3MBTL1MAPK1CYP2D6 | |
| SCHEMBL11858146 | 0.82 | ALDH1A1 (0.44) | MAPTNPSR1L3MBTL1MAPK1MGAM | |
| SCHEMBL10726885 | 0.79 | MAPT (0.51) | MAPTNPSR1L3MBTL1MAPK1CYP2D6 | |
| SCHEMBL10589007 | 0.78 | NPSR1 (0.50) | MAPTNPSR1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL2963859 | 0.77 | CYP2D6 (0.39) | MAPTNPSR1L3MBTL1MAPK1CYP2D6 | |
| SCHEMBL20399134 | 0.76 | MAPT (0.40) | MAPTNPSR1L3MBTL1MAPK1GAA | |
| SCHEMBL11567612 | 0.74 | L3MBTL1 (0.43) | MAPTNPSR1L3MBTL1MAPK1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093486-A | Side effect reduction | AKZO N.V. (NL) | 1992-03-03 | — | — | US | disclosed |
| US-4981959-A | Modified cellulose for biocompatible dialysis membranes II and process for preparation thereof | AKZO N.V. (NL) | 1991-01-01 | — | — | US | disclosed |
| US-4962140-A | Process for producing cellulosic dialysis membranes having improved biocompatibility and device for carrying out the process | AKZO N.V. (NL) | 1990-10-09 | — | — | US | disclosed |