SCHEMBL9729300

SCHEMBL9729300

CC(C)COCCCNC(c1ccccc1)C(O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.41
ALDH1A1 P00352 4/20 0.41
SCN8A Q9UQD0 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
ADRA2C P18825 2/20 0.38
CHRM2 P08172 1/20 0.38
ADRA1A P35348 1/20 0.38
RGS12 O14924 1/20 0.38
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
PKM P14618 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
NFKB1 P19838 1/20 0.38
HTR2A P28223 1/20 0.38
CYP2C19 P33261 1/20 0.38
THPO P40225 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9729205 0.84 ALDH1A1 (0.46) AOC3ALDH1A1SCN8ASMN1; SMN2TSHR
SCHEMBL9729471 0.83 ALDH1A1 (0.52) AOC3ALDH1A1SMN1; SMN2TSHR
SCHEMBL9729958 0.83 ALDH1A1 (0.59) AOC3ALDH1A1SCN8ASMN1; SMN2ADRA2C
SCHEMBL9729157 0.82 SMN1; SMN2 (0.45) AOC3ALDH1A1SMN1; SMN2ADRA2CCHRM2
SCHEMBL9729078 0.77 ALDH1A1 (0.47) AOC3ALDH1A1SMN1; SMN2ADRA2CCHRM2
SCHEMBL9728882 0.76 HPGD (0.49) AOC3ALDH1A1ADRA2CCHRM2ADRA1A
SCHEMBL9728901 0.76 ALDH1A1 (0.54) AOC3ALDH1A1ADRA2CCHRM2ADRA1A
SCHEMBL9729228 0.74 AOC3 (0.50) AOC3ALDH1A1ADRA2CCHRM2ADRA1A
SCHEMBL29433956 0.74 AOC3 (0.53) AOC3ALDH1A1ADRA2CCHRM2ADRA1A
SCHEMBL4083083 0.74 AOC3 (0.53) AOC3ALDH1A1ADRA2CCHRM2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4803200-A SHIPPING FEVER SYNDROME A. H. ROBINS COMPANY, INCORPORATED (US) 1989-02-07 US claimed
US-5171753-A Derivatives of 2-amino-1-phenylethanol having antiulcer activity A. H. ROBINS COMPANY, INCORPORATED (US) 1992-12-15 US disclosed
US-4803200-A SHIPPING FEVER SYNDROME A. H. ROBINS COMPANY, INCORPORATED (US) 1989-02-07 US disclosed