Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729205 | 0.90 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2RAB9AAOC3TSHR | |
| SCHEMBL9729078 | 0.88 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9AKDM4EAOC3 | |
| SCHEMBL9729157 | 0.88 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2RAB9AAOC3TSHR | |
| SCHEMBL9729300 | 0.83 | AOC3 (0.41) | ALDH1A1SMN1; SMN2AOC3TSHR | |
| SCHEMBL9729958 | 0.80 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KDM4EAOC3GAA | |
| SCHEMBL4083083 | 0.77 | AOC3 (0.53) | ALDH1A1RAB9AKDM4EAOC3TSHR | |
| SCHEMBL9728882 | 0.76 | HPGD (0.49) | ALDH1A1AOC3GAATSHRHPGD | |
| SCHEMBL9728901 | 0.76 | ALDH1A1 (0.54) | ALDH1A1RAB9AKDM4EAOC3TSHR | |
| SCHEMBL9729228 | 0.74 | AOC3 (0.50) | ALDH1A1RAB9AKDM4EAOC3TSHR | |
| SCHEMBL9729241 | 0.74 | AOC3 (0.46) | ALDH1A1RAB9AKDM4EAOC3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171753-A | Derivatives of 2-amino-1-phenylethanol having antiulcer activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-12-15 | — | — | US | disclosed |