Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DOCK5 | Q9H7D0 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003055 | 0.90 | TACR1 (0.48) | CXCR3MAPTTACR1MEN1CYP3A4 | |
| SCHEMBL9003052 | 0.90 | TACR1 (0.48) | CXCR3MAPTTACR1MEN1CYP3A4 | |
| SCHEMBL9268452 | 0.90 | TACR1 (0.48) | CXCR3MAPTTACR1MEN1CYP3A4 | |
| SCHEMBL9729281 | 0.88 | MEN1 (0.43) | DPP4CXCR3SIGMAR1CHRM2CHRM3 | |
| SCHEMBL9729536 | 0.88 | CCR5 (0.42) | DPP4CXCR3SIGMAR1CHRM2CHRM3 | |
| SCHEMBL9729490 | 0.82 | TACR1 (0.48) | MAPTTACR1MEN1CYP3A4TSHR | |
| SCHEMBL8874365 | 0.80 | GAA (0.44) | DPP4MAPTTACR1MEN1CYP3A4 | |
| SCHEMBL9730167 | 0.78 | MEN1 (0.51) | SIGMAR1CHRM2CHRM3CCR5MAPT | |
| SCHEMBL9729134 | 0.77 | TACR1 (0.39) | DPP4CXCR3SIGMAR1MAPTTACR1 | |
| SCHEMBL8875025 | 0.76 | GAA (0.46) | DPP4TACR1DRD2DRD3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |