Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003055 | 0.89 | TACR1 (0.48) | MEN1CYP3A4MAPTTSHRTACR1 | |
| SCHEMBL9268452 | 0.89 | TACR1 (0.48) | MEN1CYP3A4MAPTTSHRTACR1 | |
| SCHEMBL9003052 | 0.89 | TACR1 (0.48) | MEN1CYP3A4MAPTTSHRTACR1 | |
| SCHEMBL9729382 | 0.88 | DPP4 (0.46) | MEN1CYP3A4MAPTTSHRTACR1 | |
| SCHEMBL9729536 | 0.87 | CCR5 (0.42) | MEN1CYP3A4MAPTTSHRTACR1 | |
| SCHEMBL8874365 | 0.81 | GAA (0.44) | MEN1CYP3A4MAPTTSHRTACR1 | |
| SCHEMBL9730126 | 0.81 | TACR1 (0.51) | MEN1CYP3A4MAPTTSHRTACR1 | |
| SCHEMBL8875025 | 0.78 | GAA (0.46) | TACR1DPP4 | |
| SCHEMBL9730176 | 0.77 | TACR1 (0.53) | MEN1CYP3A4MAPTTSHRTACR1 | |
| SCHEMBL9729134 | 0.76 | TACR1 (0.39) | MEN1CYP3A4MAPTTSHRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |