Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003052 | 0.84 | TACR1 (0.48) | TACR1CXCR3CYP3A4TSHRCYP2C19 | |
| SCHEMBL9268452 | 0.84 | TACR1 (0.48) | TACR1CXCR3CYP3A4TSHRCYP2C19 | |
| SCHEMBL9003055 | 0.84 | TACR1 (0.48) | TACR1CXCR3CYP3A4TSHRCYP2C19 | |
| SCHEMBL9729536 | 0.81 | CCR5 (0.42) | TACR1CXCR3SIGMAR1CYP3A4TSHR | |
| SCHEMBL8875025 | 0.78 | GAA (0.46) | TACR1DRD2DRD3FUCA1DPP4 | |
| SCHEMBL9729382 | 0.77 | DPP4 (0.46) | TACR1CXCR3SIGMAR1CYP3A4TSHR | |
| SCHEMBL8874365 | 0.77 | GAA (0.44) | TACR1CYP3A4TSHRCYP2C19ALDH1A1 | |
| SCHEMBL9729281 | 0.76 | MEN1 (0.43) | TACR1CXCR3SIGMAR1CYP3A4TSHR | |
| SCHEMBL8874334 | 0.75 | TACR1 (0.40) | TACR1SIGMAR1CYP3A4TSHRCYP2C19 | |
| SCHEMBL8875253 | 0.73 | CHRM4 (0.44) | TACR1SCN9ASIGMAR1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |