Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | KIF11 | P52732 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729514 | 0.80 | LMNA (0.43) | CHRM3KIF11LMNAKCNH2 | |
| SCHEMBL27278401 | 0.80 | KIF11 (0.39) | CHRM3CYP19A1SCN5ASCN9AKIF11 | |
| SCHEMBL9729319 | 0.79 | CHRM3 (0.46) | CHRM3CYP19A1KIF11SMN1; SMN2 | |
| SCHEMBL27278356 | 0.77 | KIF11 (0.37) | CHRM3CYP19A1SCN5ASCN9AKIF11 | |
| SCHEMBL19884937 | 0.77 | SMN1; SMN2 (0.47) | CHRM3MAPK1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29949230 | 0.76 | KIF11 (0.40) | CYP19A1SCN5ASCN9AKIF11 | |
| Hydrochloric Acid SCHEMBL27076803 | 0.76 | KIF11 (0.40) | CYP19A1SCN5ASCN9AKIF11 | |
| Hydrochloric Acid SCHEMBL26965558 | 0.76 | KIF11 (0.40) | CYP19A1SCN5ASCN9AKIF11 | |
| SCHEMBL11618396 | 0.75 | KIF11 (0.49) | CHRM3CYP19A1SCN5ASCN9AKIF11 | |
| SCHEMBL1155523 | 0.72 | CYP19A1 (0.50) | CHRM3CYP19A1SCN5ASCN9AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |