Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | KIF11 | P52732 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729433 | 0.80 | CHRM3 (0.46) | LMNAKIF11KCNH2CHRM3 | |
| SCHEMBL9729319 | 0.80 | CHRM3 (0.46) | ACHEKIF11CHRM2CHRM3EDNRB | |
| SCHEMBL19884937 | 0.78 | SMN1; SMN2 (0.47) | CYP2D6CYP3A4CYP2C9CYP2C19CHRM2 | |
| SCHEMBL2066853 | 0.77 | KIF11 (0.49) | LMNAACHEKIF11CYP2D6CYP3A4 | |
| SCHEMBL8784973 | 0.73 | ACHE (0.52) | LMNAACHEKIF11CYP2D6CYP3A4 | |
| SCHEMBL31589254 | 0.73 | ACHE (0.52) | LMNAACHEKIF11CYP2D6CYP3A4 | |
| SCHEMBL3677112 | 0.73 | ACHE (0.52) | LMNAACHEKIF11CYP2D6CYP3A4 | |
| SCHEMBL6618203 | 0.71 | HTT (0.55) | LMNAKIF11CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL5876419 | 0.71 | HTT (0.55) | LMNAKIF11CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL6618200 | 0.71 | HTT (0.55) | LMNAKIF11CYP2D6CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |