Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729514 | 0.80 | LMNA (0.43) | CHRM3KIF11CHRM2ACHEEDNRB | |
| SCHEMBL16561969 | 0.79 | CHRM3 (0.49) | CHRM3KCNN4CYP19A1KIF11CCR2 | |
| SCHEMBL9729433 | 0.79 | CHRM3 (0.46) | CHRM3CYP19A1KIF11SMN1; SMN2 | |
| SCHEMBL5876465 | 0.79 | KMT2A (0.49) | CHRM3KCNN4KIF11CHRM2NR3C2 | |
| SCHEMBL5875787 | 0.77 | KMT2A (0.46) | KCNN4CYP19A1SMN1; SMN2 | |
| SCHEMBL19884937 | 0.77 | SMN1; SMN2 (0.47) | CHRM3KCNN4CHRM2SMN1; SMN2 | |
| SCHEMBL14415705 | 0.73 | KIF11 (0.49) | CHRM3KCNN4CYP19A1KIF11CCR2 | |
| SCHEMBL5687838 | 0.73 | CCR2 (0.45) | CHRM3KCNN4CYP19A1KIF11CCR2 | |
| SCHEMBL24824473 | 0.72 | KCNN4 (0.52) | CHRM3KCNN4CYP19A1KIF11ACHE | |
| SCHEMBL22012213 | 0.72 | KCNN4 (0.52) | CHRM3KCNN4CYP19A1KIF11ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |