Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 16/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729610 | 0.93 | RYR2 (0.43) | RYR2MTNR1ACYP19A1KCNH2 | |
| Formamide SCHEMBL9730166 | 0.86 | ALOX5 (0.39) | RYR2 | |
| SCHEMBL9730758 | 0.79 | RYR2 (0.44) | RYR2MTNR1ACYP19A1KCNH2 | |
| SCHEMBL9729947 | 0.77 | RYR2 (0.44) | RYR2CYP19A1KCNH2 | |
| SCHEMBL9729564 | 0.75 | ALOX5 (0.46) | RYR2MTNR1AKCNH2 | |
| Formamide SCHEMBL9729847 | 0.74 | MTNR1A (0.57) | MTNR1ACYP19A1 | |
| Hydrochloric Acid SCHEMBL9275186 | 0.74 | METAP1 (0.49) | RYR2CYP19A1KCNH2 | |
| SCHEMBL9085563 | 0.72 | DRD2 (0.54) | RYR2KCNH2 | |
| Hydrochloric Acid SCHEMBL752467 | 0.71 | DRD2 (0.53) | RYR2KCNH2 | |
| SCHEMBL9213535 | 0.70 | RYR2 (0.49) | RYR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |