Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 12/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730758 | 0.85 | RYR2 (0.44) | RYR2KCNH2CYP19A1CYP26A1 | |
| SCHEMBL9729610 | 0.83 | RYR2 (0.43) | RYR2KCNH2CYP19A1CYP26A1 | |
| Hydrochloric Acid SCHEMBL9275186 | 0.82 | METAP1 (0.49) | RYR2KCNH2CYP19A1CYP26A1 | |
| SCHEMBL9085563 | 0.77 | DRD2 (0.54) | RYR2KCNH2DRD2DRD3 | |
| Formamide SCHEMBL9729568 | 0.77 | RYR2 (0.41) | RYR2KCNH2CYP19A1 | |
| SCHEMBL9729564 | 0.76 | ALOX5 (0.46) | RYR2KCNH2 | |
| Hydrochloric Acid SCHEMBL752467 | 0.76 | DRD2 (0.53) | RYR2KCNH2DRD2DRD3 | |
| SCHEMBL14249026 | 0.73 | NCF1 (0.36) | — | |
| SCHEMBL9213535 | 0.72 | RYR2 (0.49) | RYR2KCNH2 | |
| SCHEMBL9213539 | 0.70 | RYR2 (0.47) | RYR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5156675-A | Dye, water, cosolvents, fast drying | XEROX CORPORATION (US) | 1992-10-20 | — | — | US | disclosed |
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |