Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464770 | 0.83 | HTR1A (0.67) | HTR1AKDM4CMTNR1AENPP2USP2 | |
| SCHEMBL9464927 | 0.82 | HTR1A (0.63) | HTR1AKDM4CMTNR1AENPP2USP2 | |
| SCHEMBL5226604 | 0.82 | MTNR1A (0.61) | HTR1AKDM4CMTNR1ANQO2MTNR1B | |
| SCHEMBL5172931 | 0.81 | HTR1A (0.56) | HTR1AKDM4CENPP2USP2CYP3A4 | |
| SCHEMBL8103275 | 0.79 | HTR1A (0.56) | HTR1AKDM4CENPP2USP2CYP3A4 | |
| Benzene SCHEMBL9667571 | 0.79 | HTR1A (0.65) | HTR1AKDM4CENPP2 | |
| Hydrochloric Acid SCHEMBL8112970 | 0.78 | HTR1A (0.55) | HTR1AKDM4CENPP2USP2CYP3A4 | |
| SCHEMBL5263983 | 0.78 | MTNR1A (0.54) | HTR1AMTNR1ANQO2MTNR1B | |
| SCHEMBL5175120 | 0.77 | HTR1A (0.54) | HTR1AKDM4CMTNR1AENPP2NQO2 | |
| SCHEMBL9729621 | 0.75 | HTR1A (0.47) | HTR1AKDM4CUSP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |