Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103275 | 0.79 | HTR1A (0.56) | HTR1AKDM4CUSP2CYP3A4 | |
| Hydrochloric Acid SCHEMBL8112970 | 0.77 | HTR1A (0.55) | HTR1AKDM4CUSP2CYP3A4 | |
| SCHEMBL5175120 | 0.76 | HTR1A (0.54) | HTR1AKDM4CUSP2CYP3A4 | |
| SCHEMBL11000702 | 0.76 | HTR1A (0.43) | HTR1AUSP2CYP3A4 | |
| SCHEMBL5226604 | 0.76 | MTNR1A (0.61) | HTR1AKDM4C | |
| Formamide SCHEMBL9729628 | 0.75 | HTR1A (0.59) | HTR1AKDM4CUSP2CYP3A4 | |
| SCHEMBL5172931 | 0.75 | HTR1A (0.56) | HTR1AKDM4CUSP2CYP3A4 | |
| SCHEMBL5223865 | 0.74 | MTNR1A (0.63) | HTR1A | |
| SCHEMBL9464927 | 0.74 | HTR1A (0.63) | HTR1AKDM4CUSP2CYP3A4 | |
| SCHEMBL9695945 | 0.73 | ALOX5 (0.74) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |