Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.38 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9729549 | 0.83 | MTNR1A (0.45) | ALOX5MTNR1AITGB3ITGA2BACLY | |
| Formamide SCHEMBL9694812 | 0.79 | ALOX5 (0.61) | ALOX5 | |
| Formamide SCHEMBL9618563 | 0.79 | ALOX5 (0.61) | ALOX5MTNR1A | |
| Formamide SCHEMBL9730166 | 0.78 | ALOX5 (0.39) | ALOX5KYAT1KYAT3AADAT | |
| Formamide SCHEMBL9845560 | 0.78 | ALOX5 (0.55) | ALOX5MTNR1AKYAT1KYAT3AADAT | |
| Formamide SCHEMBL9729847 | 0.77 | MTNR1A (0.57) | MTNR1ATP53 | |
| SCHEMBL9729641 | 0.76 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9730306 | 0.74 | ALOX5 (0.80) | ALOX5MTNR1A | |
| SCHEMBL9696255 | 0.72 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9696268 | 0.71 | ALOX5 (0.62) | ALOX5MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |