Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9729642 | 0.83 | ALOX5 (0.61) | MTNR1AALOX5ITGB3ITGA2BACLY | |
| SCHEMBL9730076 | 0.74 | ALOX5 (0.71) | MTNR1AALOX5ITGB3ITGA2BHRH3 | |
| Formamide SCHEMBL9729847 | 0.73 | MTNR1A (0.57) | MTNR1A | |
| Formamide SCHEMBL9729588 | 0.67 | ALOX5 (0.58) | MTNR1AALOX5 | |
| Formamide SCHEMBL9695907 | 0.65 | ALDH1A1 (0.60) | MTNR1ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6554194 | 0.64 | ITGB3 (0.57) | MTNR1AALOX5ITGB3ITGA2BLTB4R | |
| SCHEMBL6554201 | 0.64 | ITGB3 (0.57) | MTNR1AALOX5ITGB3ITGA2BLTB4R | |
| Formamide SCHEMBL9618563 | 0.64 | ALOX5 (0.61) | MTNR1AALOX5DRD2 | |
| Formamide SCHEMBL9694812 | 0.64 | ALOX5 (0.61) | ALOX5 | |
| SCHEMBL5346165 | 0.64 | MTNR1A (0.70) | MTNR1AALOX5ITGB3ITGA2BHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |